Description
Buy 4-AcO-DMT Online Colorado
Buy 4-AcO-DMT Online Colorado
4-AcO-DMT (O-acetylpsilocin), is a novel tryptamine that was discovered in the early 50s. Furthermore, It is an O-acetate ester of psilocin. Moreover, While there are studies done on the use of serotonin 5-HT2A agonists in treating substance/drug use disorders, the neurological basis of these effects has yet to be elucidated. Nevertheless, there is an interesting study done on the effects of 4-Aco-DMT on drug-dependent rats and mice, published in the European Journal of Neuroscience (EJN). Buy 4-AcO-DMT Online
Indication And Uses
1) Treatment Of drug Dependence
2) Management of Depression
About Drug Use
Chronic use of drugs of abuse produces changes and cellular adaptations in neurons located in the VTA (Ventral Tegmental Area) of the brain, which is part of the dopamine-mediated reward pathway. Nevertheless, These adaptations are mediated by BDNF (brain-derived neurotrophic factor) and are associated with the aversive withdrawal motivation that leads to a drug-dependent state. Furthermore, there is growing evidence that suggests that 5-HT2A receptor signaling can regulate the expression of BDNF in the brain. Moreover, Both 5-HT and TrkB signaling are involved in modulating long-term neuronal survival and plasticity but it is still unknown if these effects occur via a direct 5HT2A interaction or downstream interactions between 5HT2A.
Studies On 4-Aco-DMT
In a study done with 4-Aco-DMT, it was observed that a single administration to the VTA of rats and mice blocks the aversive conditioned response to drug withdrawal as well as the mechanism that switches the drug-naive state to a drug-dependent system. Moreover, These studies indicated that 5-HT2A agonists can be used as therapeutic agents to reverse drug dependency and inhibit the aversive withdrawal response. Nevertheless, Our batch of 4-AcO-DMT has been used in scientific research as a standard for purity analysis and has been confirmed as near 100% purity in a published paper. Buy 4-AcO-DMT Online Colorado
Side Effects
1) Vivid hallucination
2) Euphoria
3) Altered sense of personalization
4) Rapid heart rate
5) Increase blood pressure
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The most mind blowing thing you can do. After taking 2 big puffs, I was completely overtaken by vivid hallucinations. Eyes open or closed, it did not Matter, nothing can explain the blast off. My vision was pure hallucinations of lights. It was so crazy, I believe skydiving would be nothing to me now. Like I could fall asleep skydiving, after experiencing that. The come down was insane, joining back up with your body is very hard to describe, kinda uncomfortable. The vape worked fantastic, easy to use. Honestly, if you can even hold the pen to your mouth after 2 big hits, you’re a machine. As I was coming back from the trip, I kept repeating, this is not to be messed with. Please respect what this can do to you. I was not expecting such insane results, this is a very strong vape pen. No amount of research will prepare you for this. You just have to do it to see. I highly recommend this. But please respect what this can do to you.
Silas –
I got up to 7 pulls in the vape. I was flying through a tunnel made of bright neon colors like purple, orange, and blue. The tunnel was made of geometric patterns. I was seeing shapes and designs you cant even imagine. I was being comforted by a beautiful woman in a headdress made of light. She was rubbing my head like a mother would rub her child’s head. She made me feel safe and comfortable. She was also reaching out to me with her hand.
Mohan –
Thanks for the review man. It wasn’t this pen for me, that I know of, but my method worked extremely well. 2 lung fulls, not holding for more than a couple seconds, and a 3rd lung full (very long draws), holding for like 5 seconds. Then as the colors came in, I hauled another 2 or 3 times quickly, and had the hardest time blowing out the last one. What an extreme ride that was. The extra hits as you’re going in keeps you in longer. Having someone who can hand it back to you after like 3-5 minutes after the extra hits, and take another one or two, is ever better. I will toss out a warning, never, EVER, try to go back in, as you’re coming out. The overwhelming fear that comes from it, and what to me felt like almost going into convulsions, was terrifying, and very hard to calm yourself from. The lasting effect of the entire experience has been profound. Anger issues absolutely gone, and my depression disappeared. Can’t wait to try again. Thanks again for your review.
Frank –
Ok I just tried some DMT I just got. I took 2 pulls and I was gone. I say the best way to expirence DMT is with your eyes closed. I seen the Silhouettes of humanoid beings and they were maybe dancing around me. I didn’t feel alone when I was going through the “trip” I was happy to see the entities again and they were happy to see me.
I was seeling balls of light , orange ,blue and pink slowly pass by me and out-of my vision. (My eyes are closed for all of this) DMT is the best thing I’ve ever got to try. Thank you Psilocin Dispensary.
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First time try DMT. I had 2 pulls on my vape. When I blew out my 2nd pull i was instantly hallucinating. Was seeing geometric paterns and everything was moving. It last for about 10 minutes. My next time trying it I will have 4 to 5 pulls to get the true DMT experience.
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